The Fury around Benzofury: 5-APB and 6-APB

The Fury around Benzofury:  5-APB and 6-APB The phenylethylamines 5-APB (1-(benzofuran-5-yl)-propan-2-amine) and 6-APB (1-(benzofuran-6-yl)-propan-2-amine) (aka “Benzo Fury”, “Benzofury”, 5-APB, 6-APB) are two of many new psychoactive substances making the news.1-3, 7-9 The prevalence of use is unclear as these compounds are often taken with other drugs. The compounds have been detected in individuals presenting with[…]

Phencyclidine-Has The “Dust” Been Stirred Up?

Phencyclidine-Has The “Dust” Been Stirred Up? Phencyclidine (PCP) or 1-(1-phenylcyclohexyl)piperidine), a dissociative drug known by the street name “Angel Dust”, was first synthesized by Parke, Davis and Company in 1926 for use in general anesthesia both in human and veterinary medicine.1 By the mid 1960’s its use was abandoned when patients in clinical studies experienced[…]

Designer Drugs: N-benzylpiperazine (BZP) and 1-(3-trifluoromethylphenyl)piperazine (TFMPP)

Designer Drugs: N-benzylpiperazine (BZP) and 1-(3-trifluoromethylphenyl)piperazine (TFMPP) With the influx of designer drugs readily available via Internet sources laboratories across the United States are seeing an increase in cases containing these substances. N-benzylpiperazine (BZP) and 1-(3-trifluoromethylphenyl) piperazine (TFMPP) are phenylpiperazine analogues and just two of the numerous compounds available that are often referred to as[…]

Restoring Invisible and Abandoned Trials (RIAT) Proposal

Restoring Invisible and Abandoned Trials (RIAT) Proposal Restoring Invisible and Abandoned Trials (RIAT) proposal published in the British Medical Journal suggests that all clinical trials including those that are abandoned or considered “invisible” be published.1 “Invisible trials are those that have never been published. Abandoned trials are unpublished trials that sponsors are no longer actively[…]